The Causes and Consequences of Human Genomic Variation

  • Date: –16:00
  • Location: SCAS, Thunbergssalen Linneanum, Thunbergsvägen 2
  • Lecturer: Sohini Ramachandran, Fellow, SCAS. Associate Professor of Ecology and Evolutionary Biology, and Director, Center for Computational Molecular Biology, Brown University, Providence, RI
  • Website
  • Organiser: Swedish Collegium for Advanced Study (SCAS)
  • Contact person: Sandra Maria Rekanovic
  • Seminarium

Welcome to a seminar with Sohini Ramachandran who will give a talk titled The Causes and Consequences of Human Genomic Variation. Afterwards there will be time for questions. The seminar is held in English.

The human genome is 3 billion base pairs long, and a random pair of humans only differ at one one-thousandth of those base pairs. Despite this small number of differences, collections of genomic data contain detailed information about the history of our species over the last 100,000 years, regarding natural selection, population size changes, and human migration. I’ll offer a tour through my work and that of others on the processes that have generated observed present-day genetic variation, with a focus on the strong signature that population histories have left on human genomes. I’ll then move into the “consequences” of human genetic variation, by offering examples of how data-driven research in genomics can overturn long-held views on fundamental genetic processes.